Early detection of central nervous system relapse by polymerase chain reaction in children with B-precursor acute lymphoblastic leukemia
โ Scribed by V. de Haas; R. Vet; O. Verhagen; W. Kroes; H. van den Berg; C. van der Schoot
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 37 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0939-5555
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In a retrospective study, which comprised the whole Dutch childhood population of approximately 3 million children, the authors assessed the influence of an isolated meningeal relapse, occurring as first relapse, together with some patient and treatment characteristics on prognosis in 142 children w
## Background. We assessed efficacy and morbidity of chemotherapy and 1,800 cGy of hypofractionated craniospinal irradiation (CSI) in children with central nervous system (CNS) relapse following first remisssion of acute lymphoblastic leukemia (ALL). Procedure. Nineteen patients with isolated CNS r