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Early detection of amyloid aggregation using intrinsic fluorescence

โœ Scribed by Olaf J. Rolinski; Mariana Amaro; David J.S. Birch


Book ID
108072211
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
404 KB
Volume
25
Category
Article
ISSN
0956-5663

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DNA could readily associate with the aggregated forms of the โค-amyloid peptides โค(1-40) and โค(25-35), giving rise to a shift in the electrophoretic mobility of DNA. As a result, DNA was retained at the top of a 1% agarose gel. In contrast, the electrophoretic mobility of DNA was little influenced by