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Early detection of Alzheimer's disease: Probing mitochondrial function in the periphery

โœ Scribed by Lakatos, Anita; Coskun, Pinar; Ho, Jestine; Smith, Ian; Potkin, Steven; Saykin, Andrew; Blurton-Jones, Mathew

Book ID
123008005
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
48 KB
Volume
9
Category
Article
ISSN
1552-5260

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Mitochondrial structural and functional alterations appear to play to an important role in the pathogenesis of Alzheimer's disease (AD). In the present study, we used a quantitative comparative proteomic profiling approach to analyze changes in the mitochondrial proteome in AD. A triple transgenic m