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Early CNS toxicity after intrathecal methotrexate

โœ Scribed by Sanju Cyriac; Rejiv Rajendranath; T. G. Sagar


Book ID
107645315
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
347 KB
Volume
24
Category
Article
ISSN
0971-4502

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โœ Shore, T. ;Barnett, M. J. ;Phillips, G. L. ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 401 KB

## Abstract Methotrexate leukoencephalopathy is a chronic syndrome of ataxia and confusion which may progress to seizures, coma, and death. We report a fatal case of this syndrome in a patient who displayed no evidence of the typical prodrome of neurologic symptoms or signs. This patient suffered b