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Early changes in the mitochondrial membrane potential induced by MPP+ in human neuroblastoma SH-SY5Y cells

โœ Scribed by Nomura, Shohei; Muroyama, Akiko; Mitsumoto, Yasuhide


Book ID
123321531
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
73 KB
Volume
68
Category
Article
ISSN
0168-0102

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A genetic defect in complex I of the mitochondrial electron transport chain (ETC) is implicated in the etiology of Parkinson's disease (PD), and has been studied in cybrid mitochondrial transgene cells based on the SH-SY5Y neuroblastoma. We sought to characterize further the mechanisms and time cour