Characterization and time course of MPP+
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Christopher P. Fall; James P. Bennett Jr.
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Article
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1999
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John Wiley and Sons
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English
โ 223 KB
๐ 2 views
A genetic defect in complex I of the mitochondrial electron transport chain (ETC) is implicated in the etiology of Parkinson's disease (PD), and has been studied in cybrid mitochondrial transgene cells based on the SH-SY5Y neuroblastoma. We sought to characterize further the mechanisms and time cour