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Early astrocytic atrophy in the Entorhinal cortex of a triple transgenic animal model of Alzheimer's disease

โœ Scribed by Chia-Yu Yeh; Markel Olabarria; Harun N. Noristani; Alexei Verkhratsky; Jose J. Rodriguez


Book ID
118466501
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
46 KB
Volume
6
Category
Article
ISSN
1552-5260

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Concomitant astroglial atrophy and astro
โœ Markel Olabarria; Harun N. Noristani; Alexei Verkhratsky; Josรฉ J. Rodrรญguez ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 669 KB

## Abstract Astrocytes are fundamental for brain homeostasis and are at the fulcrum of neurological diseases including Alzheimer's disease (AD). Here, we monitored changes in astroglia morphology throughout the ageโ€dependent progression of AD. We used an immunohistochemical approach that allows us