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Early and Selective Induction of Apoptosis in Human Leukemic Cells by the Alkyl-Lysophospholipid ET-18-OCH3

โœ Scribed by F. Mollinedo; R. Martinezdalmau; M. Modolell


Book ID
115572843
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
442 KB
Volume
192
Category
Article
ISSN
0006-291X

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The induction of cell death in leukemic HL-60 cells by the ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3phosphocholine (ET-18-OCH 3 ; edelfosine) followed the typical apoptotic changes in ultrastructural morphology, including blebbing, chromatin condensation, nuclear membrane breakdown and exte