𝔖 Bobbio Scriptorium
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Early ADME/Tox studies and in silico screening

✍ Scribed by Albert P Li; Matthew Segall


Book ID
114383818
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
31 KB
Volume
7
Category
Article
ISSN
1359-6446

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πŸ“œ SIMILAR VOLUMES


In silico pKa Prediction and ADME Profil
✍ Gabriele Cruciani; Francesca Milletti; Loriano Storchi; Gianluca Sforna; Laura G πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 495 KB

## Abstract Improving the ADME profile of drug candidates is a critical step in lead optimization, and because p__K__~a~ affects most ADME properties such as lipophilicity, solubility, and metabolism, it is extremely advantageous to predict p__K__~a~ in order to guide the design of new compounds. H