𝔖 Bobbio Scriptorium
✦   LIBER   ✦

E2F–HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer

✍ Scribed by Lu, Z; Luo, R Z; Peng, H; Huang, M; Nishmoto, A; Hunt, K K; Helin, K; Liao, W S-L; Yu, Y


Book ID
110070061
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
404 KB
Volume
25
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Multiple histone deacetylases repress tu
✍ Weiwei Feng; Zhen Lu; Robert Z. Luo; Xiaohong Zhang; Edward Seto; Warren S.-L. L 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 294 KB

## Abstract __ARHI__ is a maternally imprinted tumor suppressor gene that is expressed in normal breast and ovarian epithelial cells but not in most breast and ovarian cancers. Our earlier studies showed that histone deacetylases (HDACs) in complexes with transcription factors E2F1 and E2F4 play an

Epigenetic silencing of the candidate tu
✍ Beatrix Versmold; Jörg Felsberg; Thomas Mikeska; Denise Ehrentraut; Juliane Köhl 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 362 KB 👁 2 views

## Abstract Extensive hypermethylation and consecutive transcriptional silencing of tumorsuppressor genes have been documented in multiple tumor entities including breast cancer. In a microarray based genome‐wide methylation analysis of five sporadic breast carcinomas we identified a hypermethylate