✦ LIBER ✦

E2012: A novel gamma-secretase modulator-pharmacology part

✍ Scribed by Toshihide Hashimoto; Akira Ishibashi; Hiroaki Hagiwara; Yoshiyuki Murata; Osamu Takenaka; Takehiko Miyagawa

Book ID: 118466559
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 47 KB
Volume: 6
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2010.05.787

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

E2012: A novel gamma-secretase modulator

E2012: A novel gamma-secretase modulator-mechanism of action

✍ Amino, Hiroyuki; Hagiwara, Hiroaki; Murata, Yoshiyuki; Watanabe, Hideki; Sasaki, 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 63 KB

E2012, a novel gamma-secretase modulator

E2012, a novel gamma-secretase modulator, decreases plasma amyloid-beta (Aβ) levels in humans

✍ Nagy, Christa; Schuck, Edgar; Ishibashi, Akira; Nakatani, Yosuke; Rege, Bhaskar; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 46 KB

Efficacy of SPI-1865, a novel gamma-secr

Efficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models

✍ Robyn M Loureiro, Jo Ann Dumin, Timothy D McKee… 📂 Article 📅 2013 🏛 BioMed Central 🌐 English ⚖ 285 KB

The Neuronal 5-lipoxygenase Enzymatic Pa

The Neuronal 5-lipoxygenase Enzymatic Pathway as a Novel Endogenous Modulator of the Gamma-secretase Complex

✍ Domenico Pratico; Jin Chu 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 43 KB

SAR investigations on a novel class of g

SAR investigations on a novel class of gamma-secretase modulators based on a unique scaffold

✍ Austin, Wesley F.; Hubbs, Jed L.; Fuller, Nathan O.; Creaser, Steffen P.; McKee, 📂 Article 📅 2013 🏛 The Royal Society of Chemistry 🌐 English ⚖ 246 KB

Safety and pharmacokinetics of CHF5074,

Safety and pharmacokinetics of CHF5074, a novel gamma-secretase modulator, after single oral administration to healthy humans

✍ Imbimbo, Bruno P.; Mackintosh, Donna; Aponte, Tara; Frigerio, Enrico; Breda, Mas 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 48 KB