## Abstract The prognosis of esophageal squamous cell carcinoma (ESCC) patients remains very poor, which is partially due to a high rate of recurrence. This study was aimed at identifying a recurrenceβassociated epigenetic prognostic marker in patients with ESCC. We retrospectively analyzed the CpG
β¦ LIBER β¦
E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells
β Scribed by Hua Xin Si; Sai Wah Tsao; King Yin Lam; Gopesh Srivastava; Yu Liu; Yong Chuan Wong; Zhong Yin Shen; Annie Lai Man Cheung
- Book ID
- 117467053
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 198 KB
- Volume
- 173
- Category
- Article
- ISSN
- 0304-3835
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Reduction of E-cadherin strongly relates to invasiveness and metastasis in vitro. To clarify CpG methylation around the promoter region of the E-cadherin gene in oral squamous cell carcinoma (SCC), we examined the DNA samples of various human SCC cell lines and primary oral SCC tissues by methylatio