(E)-8-(3-Chlorostyryl)-1,3-7-trimethylxanthine, a Caffeine Derivative Acting Both as Antagonist of Adenosine A2A Receptors and as Inhibitor of MAO-B.
โ Scribed by Raphael Frederick; Frederic Ooms; Neal Jr. Castagnoli; Jacques P. Petzer; Jiang-Fan Feng; Michael A. Schwarzschild; Cornelis J. Van der Schyf; Johan Wouters
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 10 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Ozonolysis of the easily available monoterpenoids (โ)โ1 and (+)โ1 leads in high yield to the ketoaldehydes (โ)โ4 and (+)โ4, which serve as convenient intermediates for efficient new routes to both optical antipodes of the naturally occurring octenediol (__E__)โ2 (__Monarch__ butterfly s
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