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Dérivés C-Glycosyliques XIV. Synthèse de Glycosyl-5-Δ2-Isoxazolines

✍ Scribed by Jean M. J. Tronchet; Sonia Jaccard-Thorndahl; Liliane Faivre; Robert Massard


Publisher
John Wiley and Sons
Year
1973
Tongue
German
Weight
461 KB
Volume
56
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Treatment of terminal‐unsaturated sugars with stable aromatic nitrile oxides led to the expected Δ~2~‐isoxazolines, obtained as a mixture of two diastereoisomers epimeric at the new asymmetric carbon. One isomer (and in some cases both) has been isolated in a pure state. These compounds are potentially useful in the drug‐design of therapeutically active molecules.


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