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Dysregulation of the Receptor Activator of NF-κB Ligand and Osteoprotegerin Production Influence the Apoptosis of Multiple Myeloma Patients’ Bone Marrow Stromal Cells Co-Cultured with Myeloma Cells

✍ Scribed by Barbara Zdzisińska; Agnieszka Bojarska-Junak; Adam Walter-Croneck; Martyna Kandefer-Szerszeń


Publisher
Springer
Year
2010
Tongue
English
Weight
499 KB
Volume
58
Category
Article
ISSN
0004-069X

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## Abstract The receptor activator of nuclear factor‐kappaB ligand (RANKL) and interleukin‐1beta are osteoclast activating factors which are abnormally expressed in bone marrow stromal cells and plasma cells of multiple myeloma patients. In this work we analyzed RANKL expression in human bone marro