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Dysregulation of the Phosphatidylinositol 3-Kinase Pathway in Thyroid Neoplasia

✍ Scribed by Paes, John E.; Ringel, Matthew D.

Book ID
122060133
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
263 KB
Volume
37
Category
Article
ISSN
0889-8529

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## Abstract Phosphatidylinositol 3‐kinase (PI3‐K) is a growth factor‐activated transforming lipid (and protein) kinase, involved in cell motility and invasion, that has multiple effectors. Relatively little is known about its expression and enzymatic activity in human breast cancer. Since growth fa