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Dysregulated PI3K/Akt/PTEN pathway is a marker of a short disease-free survival in node-negative breast carcinoma

✍ Scribed by Alessandra Capodanno; Andrea Camerini; Cinzia Orlandini; Editta Baldini; Maria Letizia Resta; Generoso Bevilacqua; Paola Collecchi

Book ID: 116534691
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 1010 KB
Volume: 40
Category: Article
ISSN: 1532-8392
DOI: 10.1016/j.humpath.2009.02.005

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## Abstract ## BACKGROUND Cyclooxygenases regulate the production of prostaglandins and play a role in tumor development and progression. The authors investigated the prognostic impact of expression of the cyclooxygenase (COX) isoforms, COX‐1 and COX‐2, on disease‐free survival and progression‐fre