Retinoids are a group of vitamin A analogues that have shown promise as chemopreventive and therapeutic agents in many types of malignancy and have been entered in clinical trials with some successful results. To better understand the mechanism that mediates retinoid action and the anti-proliferativ
✦ LIBER ✦
Dyslipidemia and a reversible decrease in insulin sensitivity induced by therapy with 13-cis-retinoic acid
✍ Scribed by Heikki A. Koistinen; Anita Remitz; Helena Gylling; Tatu A. Miettinen; Veikko A. Koivisto; Pertti Ebeling
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 76 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1520-7552
- DOI
- 10.1002/dmrr.222
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## Abstract ## Background. We have previously conducted phase II trials with a combination of 13‐__cis__‐retinoic acid (13‐cRA), interferon‐α2a (IFN‐α2a), and α‐tocopherol (α‐TF) in patients with advanced oral premalignant lesions and locally advanced head and neck cancer in the adjuvant settings
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