Dysideasterols A–E, Five New Uncommon Polyhydroxylated Steroids from the South China Sea Sponge Dysidea sp.

✍ Scribed by Xiao-Chun Huang; Yue-Wei Guo; Ernesto Mollo; Guido Cimino

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: German
• Weight: 110 KB
• Volume: 88
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200590009

✦ Synopsis

Five new uncommon polyhydroxylated steroids, dysideasterols A ± E (1 ± 5), were isolated from the South China Sea sponge Dysidea sp. Their structures were established by detailed analysis of spectral data and verified via single-crystal X-ray-diffraction analysis of compound 1. The absolute configuration of 1 was determined by the modified Mosher method. a ) At 400 MHz; d referred to C 5 D 5 N (d 7.31). b ) At 400 MHz; d referred to CDCl 3 (d 7.22). c ) Data from Gunasekera and Schmitz [2]. d ) Signals may be interchanged.