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Dysibetaine: a new α,α-disubstituted α-amino acid derivative from the marine sponge Dysidea herbacea

✍ Scribed by Ryuichi Sakai; Chie Oiwa; Kojiroh Takaishi; Hisao Kamiya; Michito Tagawa

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
209 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new ct,o~-disubstituted ct-amino acid derivative, dysibetaine (1), was isolated from an aqueous extract of the marine sponge Dysidea herbacea collected in Yap, Micronesia. The structure of 1, (2R*,4R*)-2-(trimethylammonium)methyl-4-hydroxy-5-oxoprolinate, was determined by spectral methods and X-ray crystallography.

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