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Dynamin II Associates with Grb2 SH3 Domain in Ras Transformed NIH3T3 Cells

โœ Scribed by Sun Y. Yoon; Woo S. Koh; Myung K. Lee; Young M. Park; Mi Y. Han


Book ID
115580295
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
409 KB
Volume
234
Category
Article
ISSN
0006-291X

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Grb2 dominantly associates with dynamin
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## Abstract The two SH3 domains and one SH2 domain containing adaptor protein Grb2 is an essential element of the __Ras__ signaling pathway in multiple systems. The SH2 domain of Grb2 recognizes and interacts with phosphotyrosine residues on activated tyrosine kinases, whereas the SH3 domains bind