Age-related changes in DNA synthesis sti
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Akihito Ishigami; George S. Roth
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Article
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1994
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John Wiley and Sons
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English
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We examined epinephrine-and isoproterenol-stimulated DNA synthesis in primary cultured hepatocytes from 6-, 12-, and 24-month-old rats. Epinephrinestimulated DNA synthesis in 6-month-old rat hepatocytes began after 20 h and reachcd a maximum at 50 h. Similarly, isoproterenol-stimulated DNA synthesis