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Dynamics of regulatory T cells and plasmacytoid dendritic cells as immune markers for virological response in pegylated interferon-α and ribavirin therapy for chronic hepatitis C patients

✍ Scribed by Tatsuya Kanto; Michiyo Inoue; Tsugiko Oze; Masanori Miyazaki; Mitsuru Sakakibara; Naruyasu Kakita; Tokuhiro Matsubara; Koyo Higashitani; Hideki Hagiwara; Sadaharu Iio; Kazuhiro Katayama; Eiji Mita; Akinori Kasahara; Naoki Hiramatsu; Tetsuo Takehara; Norio Hayashi

Publisher: Springer Japan
Year: 2011
Tongue: English
Weight: 424 KB
Volume: 47
Category: Article
ISSN: 0944-1174
DOI: 10.1007/s00535-011-0466-y

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## Abstract A combination of pegylated interferon α (PEG‐IFNα) and ribavirin has been used widely. Enhancement of immune response against hepatitis C virus (HCV) is known to be involved in the efficacy of the combination therapy. The aim of the study was to elucidate whether the frequency or functi