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Dynamics of microtubules visualized by darkfield microscopy: Treadmilling and dynamic instability

✍ Scribed by Hotani, Hirokazu ;Horio, Tetsuya


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
798 KB
Volume
10
Category
Article
ISSN
0886-1544

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Microtubules (MTs) contribute to the directional locomotion of many cell types through an unknown mechanism. Previously, we showed that low concentrations (Ο½200 nM) of nocodazole or taxol reduced the rate of locomotion of NRK fibroblasts over 60% without altering MT polymer level [Liao et al., 1995: