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Dynamics of Global Gene Expression Changes during Mouse Preimplantation Development

✍ Scribed by Toshio Hamatani; Mark G. Carter; Alexei A. Sharov; Minoru S.H. Ko

Book ID
117795485
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
1015 KB
Volume
6
Category
Article
ISSN
1534-5807

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A fundamental problem in early mammalian development is the transformation of the highly differentiated oocyte into the totipotent blastomeres by the 2-cell stage. This remarkable transformation probably entails reprogramming the pattern of gene expression. The maternal-to-zygotic transition occurs