✦ LIBER ✦

Dynamics of clomethiazole edisylate interaction with plastic infusion systems

✍ Scribed by Elizabeth A. Kowaluk; Michael S. Roberts; Alan E. Polack

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 588 KB
Volume: 73
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600730111

No coin nor oath required. For personal study only.

✦ Synopsis

The dynamics of the interaction of clomethiazole edisylate (I) with polyvinyl chloride and cellulose propionate, the main plastics used in the manufacture of infusion bags and sets, was examined. An experimental system in which the plastic was either open or closed to the environment was used to determine the relative contribution of the sorption and permeation processes to loss from solutions of clomethiazole edisylate (I) in contact with the plastic infusion systems. Sorption by the Heminevrin, batch FL1911 lot D106; Astra Pharmaceuticals, Sodertalje, Metrohm Hensau E520 pH meter. 3 Viaflex (polyvinyl chloride), code AHB8098 empty container, 500 mL, batch Sweden.

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