Dynamic change of T315I BCR-ABL kinase d
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Wan-Seok Kim; Dongho Kim; Dong-Wook Kim; Il-Young Kweon; Soo-Hyun Kim; Hyun-Gyun
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Article
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2009
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John Wiley and Sons
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English
โ 212 KB
๐ 1 views
## Abstract We analysed the dynamic change of imatinibโresistant mutations in BCRโABL kinase domain focusing on T315I mutation during dasatinib or nilotinib therapy. Fiftyโfive imatinibโresistant chronic myeloid leukaemia patients (32 patients with imatinibโresistant mutations and 23 patients witho