Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential

Three-Dimensional Culture with Stiff Mic

Three-Dimensional Culture with Stiff Microstructures Increases Proliferation and Slows Osteogenic Differentiation of Human Mesenchymal Stem Cells

✍ John M. Collins; Perla Ayala; Tejal A. Desai; Brenda Russell 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

Stem cells are regulated not only by soluble stimuli but also the less well studied physical microenvironment. [1] The physical niche is a combination of structural, cellular, and biochemical components that vary among tissues and contribute to control proliferation and differentiation. [2] Cells fu