๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Dynamic reoptimization of a fed-batch fermentor

โœ Scribed by Mahesh S. Iyer; Theodore F. Wiesner; R. Russell Rhinehart


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
188 KB
Volume
63
Category
Article
ISSN
0006-3592

No coin nor oath required. For personal study only.

โœฆ Synopsis


Traditionally, fed-batch biochemical process optimization and control use complicated models and off-line optimizers with no on-line model adaptation and re-optimization. This work demonstrates the applicability, effectiveness, and economic potential, of a simple phenomenological model for modeling, and a novel optimizer for on-line re-optimization and control of an aerobic fed-batch fermentor.


๐Ÿ“œ SIMILAR VOLUMES


Fed-batch fermentor synthesis of 3-dehyd
โœ Kai Li; Mark R. Mikola; K. M. Draths; R. Mark Worden; J. W. Frost ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB ๐Ÿ‘ 2 views

3-Dehydroshikimic acid (DHS), in addition to being a potent antioxidant, is the key hydroaromatic intermediate in the biocatalytic conversion of glucose into aromatic bioproducts and a variety of industrial chemicals. Microbial synthesis of DHS, like other intermediates in the common pathway of arom

Dynamic optimization of hybridoma growth
โœ Sanjeev Dhir; K. John Morrow Jr.; R. Russell Rhinehart; Theodore Wiesner ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 180 KB ๐Ÿ‘ 2 views

This study addressed the problem of maximizing cell mass and monoclonal antibody production from a fed-batch hybridoma cell culture. We hypothesized that inaccuracies in the process model limited the mathematical optimization. On the basis of shaker flask data, we established a simple phenomenologic