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Dynamic regulation of gene expression by the Flt-1 kinase and Matrigel in endothelial tubulogenesis

✍ Scribed by Satsuki Kobayashi; Emi Ito; Reiko Honma; Yoshihisa Nojima; Masabumi Shibuya; Shinya Watanabe; Yoshiro Maru


Book ID
116981251
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
741 KB
Volume
84
Category
Article
ISSN
0888-7543

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Down-regulation of Flt-1 gene expression
✍ J. Mezquita; B. Mezquita; M. Pau; C. Mezquita πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 218 KB

## Abstract The mechanisms involved in the anti‐angiogenic actions of the proteasome inhibitors are poorly understood. Here, we report that the gene expression of the VEGF receptor Flt‐1 (vascular endothelial growth factor receptor 1) was down‐regulated by the reversible proteasome inhibitor MG262