The eukaryotic cell nucleus is a membrane-enclosed compartment containing the genome and associated molecules supported by a highly insoluble filamentous network known as the nucleoskeleton or nuclear matrix. The nuclear matrix is believed to play roles in maintaining nuclear architecture and organi
Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins
β Scribed by Sigal, Alex; Milo, Ron; Cohen, Ariel; Geva-Zatorsky, Naama; Klein, Yael; Alaluf, Inbal; Swerdlin, Naamah; Perzov, Natalie; Danon, Tamar; Liron, Yuvalal
- Book ID
- 109937983
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 586 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1552-4450
- DOI
- 10.1038/nmeth892
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## Abstract Nuclear receptorβbinding SETβdomainβcontaining protein 1 (__NSD1__), a culprit gene for Sotos syndrome, contains a su(var)3β9, enhancerβofβzeste, trithorax (SET) domain that is responsible for histone methyltransferase activity and other domains such as plant homeodomain (PHD) and proli