Dynamic properties of the colicin E1 ion channel
β Scribed by W.A. Cramer; Y.-L. Zhang; S. Schendel; A.R. Merrill; H.Y. Song; C.V. Stauffacher; F.S. Cohen
- Book ID
- 109318019
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 844 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0378-1097
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## Abstract The molecularity of the ion channel formed by peptide fragments of colicin has taken on particular significance since the length of the active peptide has been shown to be less than 90 amino acids and the lumen size at least 8 Γ . Cell survival experiments show that killing by colicin ob
Base substitutions have been introduced into the segment of the colicin E1 gene corresponding to the polypeptide region between the 404th and the 502nd residues which was considered to participate in colicin E1 export and bacteriocin activity. The methods used were in vitro localized mutagenesis wit