Dynamic Kinetic Resolution of α-Amino Acid Esters in the Presence of Aldehydes
✍ Scribed by Daniel A. Schichl; Stephan Enthaler; Wolfgang Holla; Thomas Riermeier; Udo Kragl; Matthias Beller
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 211 KB
- Volume
- 2008
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract We have succeeded in the enzymatic synthesis of (__R__)‐α‐aminobutyric acid from racemic α‐aminobutyronitrile. This has been demonstrated by the use of non‐stereoselective nitrile hydratase (NHase) from __Rhodococcus opacus__ 71D, D‐aminopeptidase from __Ochrobactrum anthropi__ C1‐38 an
Racemic amino acids were resolved by lipase via hydrolysis of their esters. Lipases (Pseudomonas lipase from Amano PS, Rhizopus lipase from Serva, and porcine pancrease lipase from Sigma) could selectively hydrolyze the L-amino acid esters in aqueous solution with high reactivities and selectivities