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Dynamic Kinetic Resolution of 1,3-Dihydro-2H-isoindole-1-carboxylic Acid Methyl Ester: Asymmetric Transformations toward Isoindoline Carbamates

✍ Scribed by Morán-Ramallal, Roberto; Gotor-Fernández, Vicente; Laborda, Pedro; Sayago, Francisco J.; Cativiela, Carlos; Gotor, Vicente


Book ID
111872726
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
254 KB
Volume
14
Category
Article
ISSN
1523-7060

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Dynamic Enzymatic Kinetic Resolution of
✍ Jörg Pietruszka; Robert Christian Simon; Fabian Kruska; Manfred Braun 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

## Abstract A new reaction setup for kinetic enzymatic resolution was established and is demonstrated for the case of the hydrolase‐catalysed conversion of methyl 2,3‐dihydro‐1__H__‐indene‐1‐carboxylate (**1**) in conjunction with a base‐catalysed racemisation. The system allows controlled racemisa