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Dynamic Kinetic Resolution and Desymmetrization Processes: A Straightforward Methodology for the Enantioselective Synthesis of Piperidines.

✍ Scribed by Mercedes Amat; Oriol Bassas; Nuria Llor; Margalida Canto; Maria Perez; Elies Molins; Joan Bosch

Publisher
John Wiley and Sons
Year
2007
Weight
45 KB
Volume
38
Category
Article
ISSN
0931-7597

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Dynamic Kinetic Resolution and Desymmetr
Dynamic Kinetic Resolution and Desymmetrization Processes: A Straightforward Methodology for the Enantioselective Synthesis of Piperidines
✍ Mercedes Amat; Oriol Bassas; Núria Llor; Margalida Cantó; Maria Pérez; Elies Mol 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB

## Abstract A straightforward procedure for the synthesis of enantiopure polysubstituted piperidines is reported. It involves the direct generation of chiral non‐racemic oxazolo[3,2‐__a__]piperidone lactams that already incorporate carbon substituents on the heterocyclic ring and the subsequent rem