𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dynamic Kinetic Asymmetric Transformation (DYKAT) by Combined Amine- and Transition-Metal-Catalyzed Enantioselective Cycloisomerization

✍ Scribed by Gui-Ling Zhao; Farman Ullah; Luca Deiana; Shuangzheng Lin; Qiong Zhang; Junliang Sun; Ismail Ibrahem; Pawel Dziedzic; Armando Córdova

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
253 KB
Volume
16
Category
Article
ISSN
0947-6539

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The first examples of one‐pot highly chemo‐ and enantioselective dynamic kinetic asymmetric transformations (DYKATs) involving α,β‐unsaturated aldehydes and propargylated carbon acids are presented. These DYKATs, which proceed by a combination of catalytic iminium activation, enamine activation, and Pd^0^‐catalyzed enyne cycloisomerization, give access to functionalized cyclopentenes with up to 99 % ee and can be used for the generation of all‐carbon quaternary stereocenters.

📜 SIMILAR VOLUMES

ChemInform Abstract: Dynamic Kinetic Res
ChemInform Abstract: Dynamic Kinetic Resolution and Asymmetric Transformations by Enzyme—Metal Combinations
✍ Mahn-Joo Kim; Yangsoo Ahn; Jaiwook Park 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 15 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v