✦ LIBER ✦

Dynamic imaging of contrast enhancement in brain tumors

✍ Scribed by P. R. Bullock; P. Mansfield; P. Gowland; B. S. Worthington; J. L. Firth

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 267 KB
Volume: 19
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910190217

No coin nor oath required. For personal study only.

✦ Synopsis

Gadolinium-DTPA has been shown to be a good probe for demonstrating defects in the blood-brain barrier, but it has a rapid rate of elimination so that peak circulating levels are short-lived. In this study ultrafast echo-planar imaging has been used in combination with a bolus injection of gadolinium-DTPA to evaluate perfusion within brain tumors and to assess the degree of disruption of the blood-brain barrier. The temporal profile of enhancement may allow discrimination between different tumor types.

📜 SIMILAR VOLUMES

Quantification of endothelial permeabili

Quantification of endothelial permeability, leakage space, and blood volume in brain tumors using combined T1 and T2* contrast-enhanced dynamic MR imaging

✍ X.P. Zhu; K.L. Li; I.D. Kamaly-Asl; D.R. Checkley; J.J.L. Tessier; J.C. Waterton 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 536 KB

Comparison of BOLD contrast and Gd-DTPA

Comparison of BOLD contrast and Gd-DTPA dynamic contrast-enhanced imaging in rat prostate tumor

✍ Lan Jiang; Dawen Zhao; Anca Constantinescu; Ralph P. Mason 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 420 KB

## Abstract The microcirculation and oxygenation of a tumor play important roles in its responsiveness to cytotoxic treatment, and noninvasive assessments of its vascular properties may have prognostic value. Dynamic contrast‐enhanced (DCE) ^1^H MRI based on infusion of Gd‐DTPA, and blood oxygen le

Postoperative contrast enhancement in pa

Postoperative contrast enhancement in patients with brain tumor

✍ Leon A. Weisberg 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

Postoperative contrast enhancement in pa

Postoperative contrast enhancement in patients with brain tumor

✍ Dr J. Gregory Caincross; J. H. Warwick Pexman; Michel P. Rathbone; Ronaldo F. De 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 447 KB

Amide proton transfer (APT) contrast for

Amide proton transfer (APT) contrast for imaging of brain tumors

✍ Jinyuan Zhou; Bachchu Lal; David A. Wilson; John Laterra; Peter C.M. van Zijl 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB

## Abstract In this work we demonstrate that specific MR image contrast can be produced in the water signal that reflects endogenous cellular protein and peptide content in intracranial rat 9L gliosarcomas. Although the concentration of these mobile proteins and peptides is only in the millimolar r

Microvessel density estimation in the hu

Microvessel density estimation in the human brain by means of dynamic contrast-enhanced echo-planar imaging

✍ Jens H. Jensen; Hanzhang Lu; Matilde Inglese 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

## Abstract Animal studies have shown that in vivo estimates of microvessel density in the brain may be obtained from an MRI‐measurable index (__Q__) provided that a sufficiently high dose of an intravascular paramagnetic contrast agent is employed. __Q__ is determined from the shifts in the transv