A chiral stationary phase (CSP 1) prepared starting from (R)-4hydroxyphenylglycine and then grafting (R)-N-butanoyl-4-allyloxyphenylglycine Npropyl amide to silica gel was found to be very effective in separating the enantiomers of N-(3,5-dinitrobenzoyl)-␣-amino amides. From the chromatographic beha
✦ LIBER ✦
Dynamic HPLC on Chiral Stationary Phases: A Powerful Tool for the Investigation of Stereomutation Processes
✍ Scribed by Ilaria D'Acquarica; Francesco Gasparrini; Marco Pierini; Claudio Villani; Giovanni Zappia
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 18 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A novel chiral stationary phase (CSP) for HPLC was prepared by bonding (__R__)‐1‐phenyl‐2‐(4‐methylphenyl)ethylamine amide derivative of (__S__)‐valine to aminopropyl silica gel through a 2‐amino‐3,5‐dinitro‐1‐carboxamido‐benzene unit. The CSP was used for the separation of some amino a