Fgf-8 is one of the key signaling molecules implicated in the initiation, outgrowth, and patterning of vertebrate limbs. However, it is not clear whether FGF-8 plays similar role in development and regeneration of urodele limbs. We isolated a Fgf-8 cDNA from the Mexican axolotl (Ambystoma mexicanum)
Dynamic expression of two thrombospondins during axolotl limb regeneration
β Scribed by Jessica L. Whited; Jessica A. Lehoczky; Christina A. Austin; Clifford J. Tabin
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 954 KB
- Volume
- 240
- Category
- Article
- ISSN
- 1058-8388
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## Abstract Mitotic activity and RNA synthesis were examined in normal regenerating limbs and denervated nonβregenerating limbs of larval axolotls during the first six days after amputation. H^3^βuridine incorporation into RNA was measured by autoradiography of deoxyribonuclease treated sections. G