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Dynamic domains and geometrical properties of HIV-1 gp120 during conformational changes induced by CD4 binding

✍ Scribed by Shu-Qun Liu; Shi-Xi Liu; Yun-Xin Fu


Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
956 KB
Volume
13
Category
Article
ISSN
1610-2940

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LAV44 and LAV15 (lymphadenopathy-associated virus) peptides of the CD4-binding region of gp 120 per se bind to the CD4 receptor (Reed and Kinzel, Biochemistry 30: 4521-4528, 1991; Lasky et al., Cell 50:975-985, 1987). Depending on the environment, the LAV peptides exhibit the ability to switch coope