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Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

✍ Scribed by Smallwood, Sébastien A; Tomizawa, Shin-ichi; Krueger, Felix; Ruf, Nico; Carli, Natasha; Segonds-Pichon, Anne; Sato, Shun; Hata, Kenichiro; Andrews, Simon R; Kelsey, Gavin

Book ID
120027089
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
863 KB
Volume
43
Category
Article
ISSN
1061-4036

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## Abstract The methylation pathway, which consists of two metabolic cycles of nutrients, i.e., the methionine and folate cycles, generates __S__‐adenosylmethionine, the methyl donor for the methylation of DNA and histones. Using reverse transcription‐polymerase chain reaction, we examined the gene