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Dynamic contrast-enhanced myocardial perfusion imaging using saturation-prepared TrueFISP

✍ Scribed by Wolfgang Günther Schreiber; Melanie Schmitt; Peter Kalden; Oliver Klaus Mohrs; Karl-Friedrich Kreitner; Manfred Thelen

Book ID
102904669
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
934 KB
Volume
16
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Purpose

To develop and test a saturation‐recovery TrueFISP (SR‐TrueFISP) pulse sequence for first‐pass myocardial perfusion imaging.

Materials and Methods

First‐pass magnetic resonance imaging (MRI) of Gd‐DTPA (2 mL) kinetics in the heart was performed using an SR‐TrueFISP pulse sequence (TR/TE/α = 2.6 msec/1.4 msec/55°) with saturation preparation TD = 30 msec before the TrueFISP readout. Measurements were also performed with a conventional saturation‐recovery TurboFLASH (SRTF) pulse sequence for comparison.

Results

SR‐TrueFISP images were of excellent quality and demonstrated contrast agent wash‐in more clearly than SRTF images. The signal increase in myocardium was higher in SR‐TrueFISP than in SRTF data. Precontrast SNR and peak CNR were not significantly different between both sequences despite 57% improved spatial resolution for SR‐TrueFISP.

Conclusion

SR‐TrueFISP first‐pass MRI of myocardial perfusion leads to a substantial improvement of image quality and spatial resolution. It is well suited for first‐pass myocardial perfusion studies at cardiovascular MR systems with improved gradient hardware. J. Magn. Reson. Imaging 2002;16:641–652. © 2002 Wiley‐Liss, Inc.

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