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Dynamic behavior of the ends of growing parallel fibers in early postnatal rat cerebellum

✍ Scribed by Liljelund, Patricia ;Levine, Joel M.


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
461 KB
Volume
36
Category
Article
ISSN
0022-3034

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✦ Synopsis


The molecular layer of the cerebelalong the axon shaft. Growth cones in living slices lum contains parallel fibers, the axons of granule neuclosely resembled those observed in the fixed prepararons. We have examined the morphology and behavior of parallel fiber growth cones in the early postnatal tions. The living growth cones exhibited frequent larat cerebellum using the fluorescent tracer DiI. Paralmellopodial rearrangement and a side-to-side headlel fiber growth cones distributed into three categories waving movement. The axon proximal to the growth based on size and shape: short torpedo-like, long torcone was also dynamic. The axons curved and undupedo-like, and lamellopodial in form. The torpedolated, and mobile swellings formed along the axon like growth cones were modified by the addition of shaft. These observations show that the growth cones lamellopodia and/or filopodia, and the lamellopodial of parallel fibers are similar to growth cones described growth cones were often decorated with a filopodium.

for axons in other developing systems in terms of size, These three different growth cone morphologies were morphological characteristics, and dynamic behavior. found throughout the growing region of the molecular