DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts

Assessment of fraction of radiobiologica

Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI

✍ Tormod A. M. Egeland; Jon-Vidar Gaustad; Ida K. Vestvik; Ilana C. Benjaminsen; B 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 1000 KB

## Abstract A noninvasive method for assessment of the extent of hypoxia in experimental and human tumors is highly needed. In this study, the potential usefulness of dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) was investigated, using gadopentetate dimeglumine (Gd‐DTPA) as contra