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Dutch Resolution: Nucleation Inhibition in an Ephedrine−Cyclic Phosphoric Acid System

✍ Scribed by Loh, Joanne S. C.; van Enckevort, Willem J. P.; Vlieg, Elias; Gervais, Claire; Grimbergen, Reinier F. P.; Kaptein, Bernard


Book ID
125931036
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
153 KB
Volume
6
Category
Article
ISSN
1528-7483

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✍ Albertus D. van der Haest; Hans Wynberg; Frank J. J. Leusen; Alle Bruggink 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 569 KB

## Abstract The effects of various aromatic substituents in both ephedrine and a cyclic phosphoric acid on the quality of resolution via diastereomeric salt formation are investigated. The diastereo‐selective synthesis of a novel series of chloro‐substituted ephedrines is described. These chloroeph