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Dutch hereditary cerebral amyloid angiopathy: Structural lesions and apolipoprotein E genotype

✍ Scribed by Dr M. Bornebroek; J. Haan; S. G. Van Duinen; M. L. C. Maat-Schieman; M. A. Van Buchem; E. Bakker; C. Van Broeckhoven; R. A. C. Roos

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 468 KB
Volume: 41
Category: Article
ISSN: 0364-5134
DOI: 10.1002/ana.410410523

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## Abstract The amyloid β‐protein is a 39‐42 amino acid peptide that is deposited in senile plaques and in cerebral vessel walls in individuals with Alzheimer's disease, Down's syndrome, hereditary cerebral hemorrhage with amyloidosis–Dutch type (HCHW A‐D), and, to a much lesser extent, normal agin