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Duplication and Polymorphism in the MHC: Alu Generated Diversity and Polymorphism Within the PERB11 Gene Family

✍ Scribed by Silvana Gaudieri; Keith M. Giles; Jerzy K. Kulski; Roger L. Dawkins

Book ID: 114809948
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 772 KB
Volume: 127
Category: Article
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1997.00037.x

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The retinoblastoma gene (RB) encodes a tumor suppressor that is inactivated in a number of different types of cancer. We searched for gross alterations of this gene in tumors of the central nervous system by using Southern blot hybridization. A common alteration was found in several tumors and was m