𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Duncan William Clark, MD 1910–2007

✍ Scribed by Pascal James Imperato


Publisher
Springer US
Year
2007
Tongue
English
Weight
81 KB
Volume
33
Category
Article
ISSN
0094-5145

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A point mutation in exon 3 of the proteolipid protein (PLP) gene of the myelin-deficient (md) rat leads to a failure of oligodendrocyte maturation and early death of oligodendrocytes, resulting in dysmyelination. It has been suggested that an alternative-splice isoform of PLP, known as DM-20, might