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DUN1 defines one branch downstream of RAD53 for transcription and DNA damage repair in Saccharomyces cerevisiae

✍ Scribed by Maria-Angeles de la Torre Ruiz; Noel F. Lowndes


Book ID
117102449
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
111 KB
Volume
485
Category
Article
ISSN
0014-5793

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## Abstract The hepatocarcinogen aflatoxin B~1~ (AFB~1~) is a potent recombinagen but weak mutagen in the yeast __Saccharomyces cerevisiae__. AFB~1~ exposure induces DNA damage‐inducible genes, such as __RAD51__ and those encoding ribonucleotide reductase (RNR), through a __MEC1__ (ATR homolog)‐dep