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Ductal Carcinoma in Situ of the Breast

✍ Scribed by Rainer Fietkau

Publisher
Springer
Year
2004
Tongue
German
Weight
297 KB
Volume
180
Category
Article
ISSN
0179-7158

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Ductal carcinoma in situ of the breast
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## Abstract Ductal carcinoma in situ (DCIS) is increasing in frequency, primarily because of the increasing use of routine screening mammography. The management of DCIS has become one of the more controversial aspects in the treatment of breast cancer. Although total mastectomy provides local contr

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Ductal carcinoma in situ (DCIS) was a relatively uncommon disease process when we relied on palpation to detect breast lesions. With the advent of more widespread mammography screenings, the surgeon is faced with a welcome opportunity to prevent cancer by dealing with a precursor lesion. Discovering

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## Background: More than 50% of breast ductal carcinomas in situ (dcis) contain significant histologic necrosis, an important prognostic factor for determining recurrence and progression to invasive breast cancer. we have examined whether the mechanism of this spontaneous cell death might be apopto