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Dual role of the adaptor protein SLP-65

✍ Scribed by Sebastian Herzog; Bettina Storch; Hassan Jumaa


Book ID
111639344
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
185 KB
Volume
34
Category
Article
ISSN
0257-277X

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The adapter protein SLP-76 is required for T cell development and TCR signal transduction. SLP-76 is also expressed in NK cells, yet splenic populations of NK cells develop normally in SLP-76-deficient mice. We examined the effects of SLP-76 deficiency upon cellular activation through studies of NK